Sodium–hydrogen antiporter

The sodium–hydrogen antiporter or sodium–hydrogen exchanger is a membrane protein found in many cells, and especially in those of the nephron of the kidney. It is primarily responsible for maintaining the balance of sodium.^[1]

Isoforms

There are several isoforms of the antiporter:

References

^ VI. Mechanisms of Salt & Water Reabsorption

External links

MeSH Sodium-Hydrogen+Exchanger

Membrane transport protein: ion pumps, ATPases / ATP synthase (TC 3A2-3A3)

F- and V-type ATPase (3.A.2)

H+ (F-type)	H⁺ transporting, mitochondrial: ATP5A1, ATP5B, ATP5C1, ATP5C2, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5H, ATP5I, ATP5J, ATP5J2, ATP5L, ATP5L2, ATP5O, ATP5S

H+ (V-type)	H⁺ transporting, lysosomal: ATP6AP1, ATP6AP2, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1C1, ATP6V1C2, ATP6V1D, ATP6V1E1, ATP6V1E2, ATP6V1F, ATP6V1G1, ATP6V1G2, ATP6V1G3, ATP6V1H, ATP6V0A1, ATP6V0A2, ATP6V0A4, ATP6V0B, ATP6V0C, ATP6V0D1, ATP6V0D2, ATP6V0E TCIRG1

P-type ATPase (3.A.3)

3.A.3.1.1: Na⁺/K⁺ transporting: ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B1, ATP1B2, ATP1B3, ATP1B4, ATP1G1

3.A.3.1.2: H+/K+, H⁺/K⁺ exchanging: ATP4A, ATP4B

3.A.3.1.4: H⁺/K⁺ transporting, nongastric: ATP12A

3.A.3.2: Ca+ (SERCA, PMCA, SPCA) / Ca⁺⁺ transporting: ATP2A1, ATP2A2, ATP2A3, ATP2B1, ATP2B2, ATP2B3, ATP2B4, ATP2C1

3.A.3.5: Cu⁺⁺ transporting: ATP7A, ATP7B

3.A.3.8.8: flippase: ATP8A2

Other/ungrouped:

Na+/K+ - H+

Mg⁺⁺ transporting: ATP3
Class I, type 8: ATP8A1, ATP8B1, ATP8B2, ATP8B3, ATP8B4
Class II, type 9: ATP9A, ATP9B
Class V, type 10: ATP10A, ATP10B, ATP10D
Class VI, type 11: ATP11A, ATP11B, ATP11C
type 13: ATP13A1, ATP13A2, ATP13A3, ATP13A4, ATP13A5

see also ATPase disorders
B memb: cead, trns (1A, 1C, 1F, 2A, 3A1, 3A2-3, 3D), othr